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The disappearing mid-life crisis
Health Check
Nov 19, 2025

Global health journalist Andrew Green has been looking at the impact of US funding cuts on the global HIV response, and reports his findings from Botswana about the impact is it having on HIV and AIDS services there, and what new agreements may be reached on healthcare funding.

New research shows that the trend in human happiness is changing, with young people now experiencing more unhappiness than those in middle-age. Claudia speaks to Alex Bryson, Professor of Quantitative Social Sciences at University College London, to find out what is driving this change.

How can we reduce phantom limb pain in war amputations? Professor of anaesthesiology and pain medicine at Northwestern University, Doctor Steven Cohen, explains how Botox injections are helping Ukrainian patients recover post-amputation and improving their quality of life.

A new law in Karnataka, India will allow women a day of paid menstrual leave each month – but how is it being received? Plus, the remarkable HPV vaccination success story, and what that means for global cervical cancer rates.

Presenter: Claudia Hammond Producers: Helena Selby & Georgia Christie

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Joined by Professor of Global Health and Epidemiology at Boston University in the US, Dr Matthew Fox, Claudia hears about a mystery illness that is being investigated by health officials in Burundi, which has caused five deaths and sickened thirty-five people. So far lab analysis of the illness - which causes fever, vomiting, and diarrhoea - has been negative for Ebola and Marburg viruses, Rift Valley fever, and others.

We hear about influential analysis from Cochrane which has concluded that "breakthrough" Alzheimer's drugs are unlikely to benefit patients. Researchers said the impact was "well below" what was needed to make a difference to dementia patients' lives. However, their report has also provoked a vicious backlash from equally esteemed scientists who label it as fundamentally flawed.

We’re joined by health journalist Katie Silver in Mexico, who brings us the news that the President, Claudia Sheinbaum, has announced the details of a plan to introduce universal healthcare – no mean feat in country of 130 million people.

And we hear about an experiment that was done by academics to see if they could trick AI chatbots into believing in an entirely fake disease.

Presenter: Claudia Hammond Producer: Jonathan Blackwell


26min 28sec

The disappearing mid-life crisis

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