Claudia is joined by Caroline Williams to learn about the cutting-edge science of interoception – that’s how the brain interprets signals that come from inside our body. We find out how honing this skill can sometimes be helpful and why at other times it can have a negative impact on us.

Tuberculosis remains one of the deadliest infectious diseases worldwide but in Malawi a stage 3 trial is under way to develop a new vaccine. Our reporter Carrim Mpaweni checks-in on the trial’s progress.

Also on the show, Claudia speaks to psychotherapist Sophie Scott about how to persuade a loved one to get professional help when they don't want to.

Presenter: Claudia Hammond Producers: Katie Tomsett & Helena Selby Studio Manager: Giles Aspen

Receiving a specific type of shingles vaccine may provide a 23% lower risk of cardiovascular events like stroke or heart failure for up to 8 years. With reports of other shingles vaccines protecting against the risk of dementia, scientists are trying to understand the mechanism underlying these unintended benefits.

The WHO aim to eliminate the neglected tropical disease schistosomiasis from endemic countries by 2030, we investigate what might be standing in the way of this goal.

After 18 years and over 200 snake bites, key protective compounds have been identified in Tim Friede’s blood with the potential to make a snake antivenom with “unparalleled” protection.

Also on the show, a trial led by Professors Adalsteinn Gunnlaugsson and Per Nilsson has shown that a prostate cancer treatment regimen that takes two-and-a-half weeks is as safe and effective as longer 8-week courses, ten years on from treatment.

Plus, if you have celiac disease should you be worried about kissing someone who has just eaten gluten? A new study looks at how much gluten is exchanged in a kiss.

Presenter: Claudia Hammond Producer: Hannah Robins Assistant Producer: Katie Tomsett Researcher: Tabby Taylor Buck Studio Managers: Cath McGee and Sarah Hockley

Amidst conflict in Sudan, the world-leading Mycetoma Research Centre in Khartoum has been destroyed. We talk to the centre’s founder to find out what this means for research into the neglected disease and the struggle to proving ongoing support for patients.

As the Pan American Health Organization put into action lessons from the Covid-19 pandemic they share with us new telehealth services designed to reach the most remote communities across the Americas.

Also on the show, a reversible and non-hormonal male contraception implant has proven effective in trials lasting two years. Plus, how does the body respond when switching from a Tanzanian heritage diet to a more processed diet? And can gradual exposure to peanuts desensitize adults with severe peanut allergies?

Presenter: Claudia Hammond Producer: Hannah Robins Assistant Producer: Katie Tomsett Studio Managers: Emma Harth and Dyfan Rose

After 3 years of discussions, 194 member countries of the World Health Organisation have agreed to the text of a pandemic treaty designed to make the world safer from a future pandemic – but what could it mean in practice and how are countries held to account?

Also on the show, how treating high blood pressure can reduce the risk of dementia. Researchers have suggested it takes more than just medication; lifestyle changes are also key to lowering the risk.

We learn how Oropouche is underdiagnosed across the Americas and the impact climate has on the spread of this insect-borne virus. Plus, a new weight loss pill has been found to reduce weight and blood sugar levels in its latest trial.

Has an anecdote you read online or heard from a friend ever changed how you feel about the medical choices you make? We hear about the power of anecdotes, especially negative ones, when making a decision for your own health.

Presenter: Claudia Hammond Producers: Katie Tomsett & Hannah Robins Studio Manager: Emma Harth Production Co-ordinator: Josie Hardy

(Image:Co-chair of the negotiations and French ambassador for Global Health Anne-Claire Amprou (L) and WHO Director-General Tedros Adhanom Ghebreyesus after a consensus on the Pandemic Agreement at the WHO headquarters. Credit: CHRISTOPHER BLACK/World Health Organization/AFP via Getty Images)