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How far could gene editing go?
CrowdScience
May 6, 2022

Humans now have the ability to directly change their DNA, and gene-editing tool CRISPR has led to a new era in gene-editing. CrowdScience listener ‘Bones’ wants to know how gene-editing is currently being used and what might be possible in the future.

Gene-editing offers huge opportunities for the prevention and treatment of human diseases, and trials are currently underway in a wide range of diseases like sickle cell anaemia. CrowdScience presenter Caroline Steel finds out about some of the most promising work tackling disease before turning to consider the possibilities of using gene editing to enhance ourselves.

Will we be able to extend human longevity, swap our eye colour or improve athletic performance? And even if we can do all these things, should we?

As scientists push the boundaries of gene-editing and some people are DIY experimenting on themselves with CRISPR, we discuss the practical and ethical challenges facing this promising but potentially perilous area of science.

Produced by Melanie Brown and presented by Caroline Steel for the BBC World Service Contributors: Prof George Church Prof Waseem Qasim Jimi Olaghere Josiah Zayner Prof Joyce harper Prof Julian Suvalescu

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When will the next super-volcano erupt?

Is the world sitting on a ticking time bomb? CrowdScience listener Christel recently watched a documentary about a volcanic eruption in 536 AD that left her native Sweden under a cloud of ash for three years. It got her thinking, do we know when this could happen again?

With more than 300 volcanoes – and 24 of them listed as currently active – the Philippines is a country where trying to predict eruptions has huge real world consequences.

Presenter Anand Jagatia travels to Manila to meet the scientists at PHIVOLCS, the Philippine Institute of Volcanology and Seismology, including the head of their Volcano Monitoring and Eruption Prediction Division, Mariton Antonia Bornas, to find out how they try to predict volcanic activity in the country and help make sure communities are evacuated out of harm’s way.

He travels with the team to Taal volcano, which experienced violent eruptions in 2020 and has been active again this year, to visit the observatory monitoring for signs of future activity and to hike to the main crater of the volcano with resident volcanologist Paolo Reniva.

He also speaks to Dr George Cooper from Cardiff University in the UK about what makes a volcano a supervolcano, and to ask the all important question of if we know when this will happen again.

Presenter: Anand Jagatia

Producer: Dan Welsh

Editor: Ben Motley

(Photo: Smoke Emitting From Volcanic Mountain Against Sky - stock photo -EyeEm Mobile GmbH via Getty Images)


29min 05sec




How far could gene editing go?

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