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Why is human skin so rubbish?
CrowdScience
Aug 21, 2021

If you’ve ever fallen over and grazed your skin, maybe you wished it were made of stronger stuff. The tough hide of a rhinoceros or the protective armour of a stag beetle would do a better job. It’s a thought that’s been bothering CrowdScience listener Paul, who points out that our skin also suffers from acne, eczema and hives; it dries out; it bruises. In fact, human hide is so vulnerable that we cover our feet in other animals’ skin and our bodies in clothes just to make life more comfortable. Is this really the pinnacle of evolution?

Marnie Chesterton makes the case for the largest, fastest-growing organ, hiding in plain site on our body. Tissue Engineer Professor Sheila MacNeil from Sheffield University explains how skin manages to be breathable yet waterproof; flexible yet stronger than steel; sensitive to touch but protective against pollution and damaging UV. Skin biologist Dr Christina Philippeos from King’s College London explains how our bodies make a scar. Professor Muzlifah Haniffa has developed an atlas of the human skin – a tool to help researchers unravel the mysteries of how different skin cells interact. This atlas should help treat skin diseases in the future. Over in Tanzania’s Regional Dermatology Training Centre in Moshi, Dr Daudi Mavura talks us through a rare but devastating skin disorder called Xeroderma Pigmentosum, or XP. For children with XP, sunlight is dangerous because a mutation in the skin’s DNA repair mechanism means that UV rays can cause lesions and tumours.

Our epidermis is already multifunctional but over at Ben May Department of Cancer Research at the University of Chicago, Professor Xaioyang Wu and colleagues are looking at how much more skin could do. Personalised skin grafts may provide living drug patches to help people manage their disease, addiction or even weight.

With thanks to Dr Lynne MacTavish from Mankwe Wildlife Reserve in South Africa for describing a rhino’s skin.

Produced and presented by Marnie Chesterton.

[Image: Young and Old, dry skin Credit: Eric A. Nelson/Getty Images]

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Is the world sitting on a ticking time bomb? CrowdScience listener Christel recently watched a documentary about a volcanic eruption in 536 AD that left her native Sweden under a cloud of ash for three years. It got her thinking, do we know when this could happen again?

With more than 300 volcanoes – and 24 of them listed as currently active – the Philippines is a country where trying to predict eruptions has huge real world consequences.

Presenter Anand Jagatia travels to Manila to meet the scientists at PHIVOLCS, the Philippine Institute of Volcanology and Seismology, including the head of their Volcano Monitoring and Eruption Prediction Division, Mariton Antonia Bornas, to find out how they try to predict volcanic activity in the country and help make sure communities are evacuated out of harm’s way.

He travels with the team to Taal volcano, which experienced violent eruptions in 2020 and has been active again this year, to visit the observatory monitoring for signs of future activity and to hike to the main crater of the volcano with resident volcanologist Paolo Reniva.

He also speaks to Dr George Cooper from Cardiff University in the UK about what makes a volcano a supervolcano, and to ask the all important question of if we know when this will happen again.

Presenter: Anand Jagatia

Producer: Dan Welsh

Editor: Ben Motley

(Photo: Smoke Emitting From Volcanic Mountain Against Sky - stock photo -EyeEm Mobile GmbH via Getty Images)


29min 05sec




Why is human skin so rubbish?

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