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The Life Scientific - Ijeoma Uchegbu
Discovery
Mar 3, 2025

Imagine a nanoparticle, less that a thousandth of the width of a human hair, that is so precise that it can carry a medicine to just where it’s needed in the body, improving the drug’s impact and reducing side effects.

Ijeoma Uchegbu, Professor of Pharmaceutical Nanoscience at University College London, has spent her career with this goal in mind. She creates nanoparticles to carry medicines to regions of the body that are notoriously hard to reach, such as the back of the eye and the brain. With clinical trials in the pipeline, she hopes to treat blindness with eyedrops, transform pain relief and tackle the opioid crisis.

Ijeoma took an unconventional route into science. Growing up in the UK and in Nigeria, she tells Professor Jim Al-Khalili her remarkable life story, from being fostered by a white family in rural Kent, while her Nigerian parents finished their studies, to struggling to pay the bills through her PhD as a single mum with young children.

So passionate is Ijeoma to spread her love of science, she’s even turned to stand-up comedy to help get her message across!

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The Life Scientific: Jane Goodall

The celebrated primatologist Jane Goodall died last week at the age of 91. In tribute, we’re re-sharing this interview from 2020, where she reflects on the years she spent living with the wild chimpanzees in Gombe in eastern Tanzania and why she believes the best way to bring about change is to ‘creep into people’s hearts’.

Jane shot to fame when she appeared on the cover of National Geographic magazine in 1963 and appeared in a documentary film directed by Orson Welles. Her ground breaking observations introduced us to the social and emotional lives of wild chimpanzees and changed our view of what it is to be human. Images of her younger self play-wrestling with baby chimps make Jane feel slightly apprehensive now but at the time she didn’t give it a second thought. However, she did take care to protect her young son. Seeing distressing footage of chimps who were living in captivity, she gave up fieldwork to become an activist, working to liberate chimpanzees that were being used for medical research or sold for meat or as pets, and setting up chimp sanctuaries for animals that were no longer able to live in the wild. For the last thirty years, she has campaigned gently but relentlessly to protect wild animals and wild places, touring the world and performing on stage in front of huge audiences. Her global youth programme, Roots and Shoots has inspired and empowered millions of people to understand and respect nature, leading some to call her ‘the mother Theresa of the environment’. A label she dislikes.

Producer: Anna Buckley


26min 29sec


Sep 22, 2025
The Life Scientific: Jonathan Shepherd

Surgeons often have to deal with the consequences of violent attacks - becoming all too familiar with patterns of public violence, and peaks around weekends, alcohol-infused events and occasions that bring together groups with conflicting ideals.

Professor Jonathan Shepherd not only recognised the link between public violence and emergency hospital admissions, he actually did something about it.

As a senior lecturer in Oral and Maxillofacial Surgery in the early 1980s, Jonathan started looking into this trend - and his research revealed that most violent assaults resulting in emergency hospital treatment are not reported to police.

As a result, he devised the ‘Cardiff Model for Violence Prevention’: a programme where hospitals share data about admissions relating to violent attacks with local authorities. He also went on to study various aspects of violent assault and deliver evidence-based solutions - from alcohol restrictions in hotspots, to less breakable beer glasses in pubs.

The impacts have been significant, delivering reductions in hospital admissions and in violent attacks recorded by police; not only in Cardiff, but in cities around the world where the model is used. Today, as an Emeritus Professor of Oral and Maxillofacial Surgery at Cardiff University - where he’s also Director of their Crime, Security and Intelligence Innovation Institute - Jonathan continues to bring together the medical sector with local authorities, finding practical ways to make cities and their residents safer.

But his career, straddling the worlds of practise, science and policy, is an unusual one; here he talks to Professor Jim Al-Khalili about what drove him to make a difference.

Presentedby Jim Al-Khalili Produced by Lucy Taylor Reversion for World Service by Minnie Harrop


26min 29sec


The Life Scientific - Ijeoma Uchegbu

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