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Frances Arnold
Discovery
Sep 20, 2022

Nobel Prize winning chemist Frances Arnold left home at 15 and went to school ‘only when she felt like it’. She disagreed with her parents about the Vietnam war and drove big yellow taxis in Pittsburgh to pay the rent. Decades later, after several changes of direction (from aerospace engineer to bio-tech pioneer), she invented a radical new approach to engineering enzymes. Rather than try to design industrial enzymes from scratch (which she considered to be an impossible task), Frances decided to let Nature do the work. ‘I breed enzymes like other people breed cats and dogs’ she says.

While some colleagues accused her of intellectual laziness, industry jumped on her ideas and used them in the manufacture of everything from laundry detergents to pharmaceuticals. She talks to Jim Al-Khalili about her journey from taxi driver to Nobel Prize, personal tragedy mid-life and why advising the White House is much harder than doing scientific research.

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Mar 21, 2024
The Evidence: The science of the menopause

Millions of women around the world experience the menopause each year; it’s an important milestone, which marks the end of their reproductive years.

But every individual's experience of it is personal and unique. In some cultures, there's a stigma about this life stage – it's viewed with trepidation and as something to be dreaded. In other cultures, it's considered to be a fresh start - a time of greater freedom when women no longer have to worry about their menstrual cycles.

In this edition, recorded at Northern Ireland Science Festival in Belfast, Claudia Hammond and her expert panel take a global look at the science of the menopause and debunk some myths along the way.

As Claudia and her guests navigate their way through the menopause maze, they look at the most recent academic research in this area. They also discuss the physical and psychological symptoms, the lifestyle changes women can make and the different treatments available, including Hormone Replacement Therapy.

Claudia also speaks to the American biological anthropologist who has dedicated an impressive 35 years of her life to studying the average age of the menopause in different countries - and finds out how hot flushes vary in different cultures. She also speaks to a doctor who is working hard to make women’s health less of a taboo subject in the community where she works. And she hears from a Professor of Reproductive Science who is setting up the UK's first menopause school.

Producer: Sarah Parfitt Co-ordinator: Siobhan Maguire Editor: Holly Squire Sound engineers: Andrew Saunderson and Bill Maul Mix engineer: Bob Nettles

Image used with permission of the Northern Ireland Science Festival


49min 26sec


Frances Arnold

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