Home  >  Discovery  >  Elizabeth Fisher: Chromosomes in mice and men
Discovery
Elizabeth Fisher: Chromosomes in mice and men
Discovery
Mar 30, 2020

Elizabeth Fisher, Professor of Neurogenetics at University College London, spent 13 years getting her idea – finding a new way of studying genetic disorders – to work. She began her research career at a time, in the 1980s, when there was an explosion of interest and effort in finding out what genes did what, and which of them were responsible for giving rise to the symptoms of various neurodegenerative conditions. Elizabeth has been particularly interested in those in which there are chromosomal abnormalities, like Down syndrome and Turner syndrome, as distinct from specific genetic disorders. Her work has helped in the understanding of what’s different about the genetic make-up of people with these conditions, and what new therapies might be developed in the future.

Lizzie Fisher talks to Jim al-Khalili about how she was inspired to study genetics while standing on the red carpet, how she kept going during the 13 years it took to introduce human chromosomes into mice and why she's starting the process all over again.

More Episodes


Mar 21, 2024
The Evidence: The science of the menopause

Millions of women around the world experience the menopause each year; it’s an important milestone, which marks the end of their reproductive years.

But every individual's experience of it is personal and unique. In some cultures, there's a stigma about this life stage – it's viewed with trepidation and as something to be dreaded. In other cultures, it's considered to be a fresh start - a time of greater freedom when women no longer have to worry about their menstrual cycles.

In this edition, recorded at Northern Ireland Science Festival in Belfast, Claudia Hammond and her expert panel take a global look at the science of the menopause and debunk some myths along the way.

As Claudia and her guests navigate their way through the menopause maze, they look at the most recent academic research in this area. They also discuss the physical and psychological symptoms, the lifestyle changes women can make and the different treatments available, including Hormone Replacement Therapy.

Claudia also speaks to the American biological anthropologist who has dedicated an impressive 35 years of her life to studying the average age of the menopause in different countries - and finds out how hot flushes vary in different cultures. She also speaks to a doctor who is working hard to make women’s health less of a taboo subject in the community where she works. And she hears from a Professor of Reproductive Science who is setting up the UK's first menopause school.

Producer: Sarah Parfitt Co-ordinator: Siobhan Maguire Editor: Holly Squire Sound engineers: Andrew Saunderson and Bill Maul Mix engineer: Bob Nettles

Image used with permission of the Northern Ireland Science Festival


49min 26sec


Elizabeth Fisher: Chromosomes in mice and men

--:--
--:--