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WHO Pandemic Agreement reached
Science In Action
May 22, 2025

This week, 124 countries agreed at the World Health Assembly in Geneva on measures aimed at preventing a future pandemic. The agreement very strongly favours a “One Health” approach, appreciating how so many potential pathogens originate in human-animal interactions. Still to agree on the terms of how to share pathogens and information with global science and vaccine researchers, eventually the treaty will need to be signed by at least 60 countries. But can the inequity between countries of the global south and north, and issues of intellectual property, be bridged?

A new study on origins of the Nigerian mpox epidemic points strongly to zoonotic crossovers and mobility of wildlife in West Africa. Edyth Parker of Redeemer’s University in Nigeria describes their phylogenetic tree.

Can the bovine form of H5N1 flu infect pigs, and could domestic pig populations then provide a crucible for further variants to develop? Jürgen Richt of Kansas State University and colleagues have been investigating. We need to keep up vigilance.

Lucy van Dorp of University College London, working with a consortium including London’s Crick Institute, has been looking at a moment in the past when human activity provided an opportunity for a bacterial human pathogen to change its lifestyle. According to their phylogenetic tree, the bacterium Borrelia recurrentis (which causes louse-borne relapsing fever in humans) adapted and moved from ticks to human body lice around about the same time as humans started using woollen clothing.

And Susan Lieberman, VP for International Policy at the Wildlife Conservation Society, was in the trenches of the Pandemic Agreement negotiations, and shares some of her hopes for its success.

Image: World Health Assembly formally adopts by consensus world's first Pandemic Agreement, Geneva, Switzerland - 20 May 2025 Image Credit: Magali Girardin via EPA-EFE/Shutterstock

Presenter: Roland Pease Producer: Alex Mansfield

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Presenter: Roland Pease Producer: Alex Mansfield Production Coordinator: Jasmine Cerys George and Josie Hardy

Photo: A domestic dog receives a rabies vaccine during a mass vaccination in Bunda, Tanzania, October 8, 2012. (Chris Sweda/Chicago Tribune/Tribune News Service via Getty Images)


38min 45sec


May 1, 2025
Scientists of the world unite

Scientists from around the world have gathered together at the annual European Geosciences Union general assembly, to discuss current projects, working hypotheses and potential findings. There are nearly 18,000 in attendance this year and there is much to learn.

AMOC – the Atlantic Meridional Overturning Circulation - brings warmth to the north and cooler waters to the south in huge volumes. Climate modellers have expressed concern for its collapse (and subsequent weather chaos) as temperatures rise more generally, but others have said it is more resilient. But Stefan Rhamstorf has announced that extending the models past 2100 can show a different picture. The odds have shifted from 10% to more like 50/50 if the Paris climate target is missed.

Has such climate change ever occurred before? And if so, what drove it? Hana Jurikova and colleagues have been using novel techniques to detect a link between atmospheric CO2 levels and rapid climate change in the geological past, and explains how boron records in ancient brachiopods might give us a clue.

What of the 6.2 magnitude earthquake near Istanbul last week? Could it have been worse? Will the next one be the big one? Expert Patricia Martínez-Garzón of GFZ in Germany doesn’t quite allay the fears.

Could more lives be saved from landslides and flash floods if we could set up a warning system? Stefania Ursica hopes so, and has looked to animal behaviour to design a programme to scan networks of seismic monitoring stations’ output for the faint signals. Encoding different hunting and communication strategies – from nomadic whales to humming birds and bats, her new algorithm might be just the thing, though prediction will always be a different problem.

Presenter: Roland Pease Producer: Alex Mansfield with Sophie Ormiston Production co-ordinator: Josie Hardy

(Image: 3D render of a Topographic Map of Western Europe with the clouds from 27 January, 2025. Credit: Frank Ramspott/Getty Images)


29min 25sec

WHO Pandemic Agreement reached

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